Trending Headlines

Explainer: What is Remesivir and how does it treat COVID-19

For story suggestions or custom animation requests, contact tips@nextanimation.com.tw. Visit http://archive.nextanimationstudio.com to view News Direct’s complete archive of 3D news animations.

RESTRICTIONS: Broadcast: NO USE JAPAN, NO USE TAIWAN Digital: NO USE JAPAN, NO USE TAIWAN
SARS-CoV-2, the virus that causes COVID-19, is an RNA virus. This means the coronavirus uses nucleosides as the building blocks of its genetic material, according to University of Maryland, Baltimore County biochemist Katherine Seley-Radtke.

Writing for media outlet The Conversation, Seley-Radtke says the virus relies on an enzyme called polymerase to replicate its RNA nucleoside by nucleoside, so that it can make more copies of itself.

Gilead’s remdesivir is an antiviral and a nucleoside analogue, or a chemical compound that is structurally similar to naturally occurring nucleosides. During replication, remdesivir could trick the polymerase into mistaking the antiviral drug, which resembles adenosine, for the genuine article.

After this happens, the antiviral is taken into the new RNA strand and stops the polymerase from replicating more of the RNA, which should suppress the virus. Preliminary results from May suggest the drug improved patient survival rate and time recovery.

RUNDOWN SHOWS:
1. SARS-CoV-2 is an RNA virus and its genes are based on nucleosides
2. RNA viruses use polymerase for genome replication
3. Remdesivir is a nucleoside analogue
4. Nucleoside analogue disrupts RNA replication and suppresses virus reproduction

VOICEOVER (in English):
“SARS-CoV-2, the virus that causes COVID-19, is an RNA virus. This means the virus uses nucleosides as the building blocks of its genetic material, according to University of Maryland, Baltimore County biochemist Katherine Seley-Radtke.”

“Writing for media outlet The Conversation, Seley-Radtke says the virus relies on an enzyme called polymerase to replicate its RNA nucleoside by nucleoside, so that it can make more copies of itself.”

“Gilead’s remdesivir is an antiviral and a nucleoside analogue, or a chemical compound that is structurally similar to naturally occurring nucleosides. During replication, remdesivir could trick the polymerase into mistaking the antiviral drug, which resembles adenosine, for the genuine article.”

“After this happens, the antiviral is taken into the new RNA strand and stops the polymerase from replicating more of the RNA, which should suppress the virus. Preliminary results from May suggest the drug improved patient survival rate and time recovery.”

SOURCES: The Conversation, SatNews https://theconversation.com/remdesivir-explained-what-makes-this-drug-work-against-viruses-137751

Watch: How does Gilead’s experimental drug remdesivir work against the coronavirus?

***
—————————————-­­—————————————­-­—————-

Next Animation Studio’s News Direct service provides daily, high-quality, informative 3D news animations that fill in for missing footage and help viewers understand breaking news stories or in-depth features on science, technology, and health.

Sign up for a free trial of News Direct’s news animations at http://newsdirect.nextanimationstudio.com/trial/

To subscribe to News Direct or for more info, please visit:
http://newsdirect.nextanimationstudio.com

  • bitcoinBitcoin (BTC) $ 32,337.00
  • ethereumEthereum (ETH) $ 1,860.34
  • tetherTether (USDT) $ 1.00
  • binance-coinBinance Coin (BNB) $ 260.91
  • cardanoCardano (ADA) $ 1.14
  • xrpXRP (XRP) $ 0.550067
  • usd-coinUSD Coin (USDC) $ 1.00
  • dogecoinDogecoin (DOGE) $ 0.187817
  • polkadotPolkadot (DOT) $ 14.57
  • binance-usdBinance USD (BUSD) $ 1.00
  • uniswapUniswap (UNI) $ 16.26
  • bitcoin-cashBitcoin Cash (BCH) $ 438.25
  • litecoinLitecoin (LTC) $ 118.44
  • chainlinkChainlink (LINK) $ 16.62
  • solanaSolana (SOL) $ 26.10
  • matic-networkPolygon (MATIC) $ 1.06
  • wrapped-bitcoinWrapped Bitcoin (WBTC) $ 32,354.00
  • theta-tokenTheta Network (THETA) $ 6.12
  • stellarStellar (XLM) $ 0.231845
  • daiDai (DAI) $ 1.00
  • vechainVeChain (VET) $ 0.071007
  • ethereum-classicEthereum Classic (ETC) $ 36.01
  • internet-computerInternet Computer (ICP) $ 34.03
  • filecoinFilecoin (FIL) $ 49.11
  • moneroMonero (XMR) $ 202.56
  • tronTRON (TRX) $ 0.050620
  • eosEOS (EOS) $ 3.38
  • shiba-inuShiba Inu (SHIB) $ 0.000006
  • compound-usd-coincUSDC (CUSDC) $ 0.022103
  • amp-tokenAmp (AMP) $ 0.059063
  • cdaicDAI (CDAI) $ 0.021454
  • aaveAave (AAVE) $ 203.42
  • okbOKB (OKB) $ 8.99
  • theta-fuelTheta Fuel (TFUEL) $ 0.436613
  • leo-tokenLEO Token (LEO) $ 2.48
  • algorandAlgorand (ALGO) $ 0.739396
  • crypto-com-chainCrypto.com Coin (CRO) $ 0.089063
  • celsius-degree-tokenCelsius Network (CEL) $ 5.31
  • pancakeswap-tokenPancakeSwap (CAKE) $ 12.01
  • bitcoin-svBitcoin SV (BSV) $ 117.87
  • compound-ethercETH (CETH) $ 37.35
  • ftx-tokenFTX Token (FTT) $ 24.67
  • cosmosCosmos (ATOM) $ 8.85
  • neoNEO (NEO) $ 29.71
  • makerMaker (MKR) $ 2,254.05
  • klay-tokenKlaytn (KLAY) $ 0.794006
  • tezosTezos (XTZ) $ 2.34
  • iotaIOTA (MIOTA) $ 0.702710
  • terra-lunaTerra (LUNA) $ 4.64
  • terrausdTerraUSD (UST) $ 0.999231
  • avalanche-2Avalanche (AVAX) $ 10.49
  • safemoonSafeMoon (SAFEMOON) $ 0.000003
  • kusamaKusama (KSM) $ 179.81
  • huobi-tokenHuobi Token (HT) $ 9.23
  • hedera-hashgraphHedera Hashgraph (HBAR) $ 0.164195
  • true-usdTrueUSD (TUSD) $ 1.00
  • the-graphThe Graph (GRT) $ 0.486681
  • thorchainTHORChain (RUNE) $ 5.20
  • bittorrent-2BitTorrent (BTT) $ 0.002129
  • decredDecred (DCR) $ 101.08
  • sushiSushi (SUSHI) $ 6.73
  • huobi-btcHuobi BTC (HBTC) $ 31,956.00
  • compound-governance-tokenCompound (COMP) $ 232.63
  • wavesWaves (WAVES) $ 12.40
  • dashDash (DASH) $ 117.51
  • telcoinTelcoin (TEL) $ 0.021395
  • zcashZcash (ZEC) $ 105.80
  • chilizChiliz (CHZ) $ 0.218694
  • elrond-erd-2Elrond (EGLD) $ 59.04
  • yearn-financeyearn.finance (YFI) $ 28,264.00
  • staked-etherLido Staked Ether (STETH) $ 1,867.56
  • havvenSynthetix Network Token (SNX) $ 6.28
  • holotokenHolo (HOT) $ 0.005453
  • heliumHelium (HNT) $ 9.98
  • nemNEM (XEM) $ 0.096076
  • nearNear (NEAR) $ 2.11
  • enjincoinEnjin Coin (ENJ) $ 0.902576
  • zilliqaZilliqa (ZIL) $ 0.067823
  • mdexMdex (MDX) $ 1.60
  • paxos-standardPaxos Standard (PAX) $ 1.00
  • quant-networkQuant (QNT) $ 59.17
  • nexoNEXO (NEXO) $ 1.35
  • liquity-usdLiquity USD (LUSD) $ 1.02
  • basic-attention-tokenBasic Attention Token (BAT) $ 0.479365
  • xdce-crowd-saleXDC Network (XDC) $ 0.052952
  • blockstackStacks (STX) $ 0.607358
  • bancorBancor Network Token (BNT) $ 2.92
  • husdHUSD (HUSD) $ 0.986350
  • pirate-chainPirate Chain (ARRR) $ 3.35
  • compound-usdtcUSDT (CUSDT) $ 0.021264
  • zencashHorizen (ZEN) $ 54.22
  • bitcoin-goldBitcoin Gold (BTG) $ 34.34
  • livepeerLivepeer (LPT) $ 24.89
  • decentralandDecentraland (MANA) $ 0.433326
  • nanoNano (NANO) $ 4.26
  • digibyteDigiByte (DGB) $ 0.038496
  • fantomFantom (FTM) $ 0.215280
  • umaUMA (UMA) $ 8.75
  • harmonyHarmony (ONE) $ 0.051824
  • arweaveArweave (AR) $ 11.89
Scroll Up